Researchers believe it may be especially effective in patients with treatment-resistant depression.Īdjunctive aripiprazole was associated with a two-fold higher remission rate than adjunctive placebo. The other two-thirds are likely to fail to reach remission, and they must continue their search for an effective treatment plan.Īdding Abilify to an existing treatment plan can have positive outcomes compared to monotherapy, or treating depression with one medication at a time.Īripiprazole was found to increase the effectiveness of mirtazapine, an antidepressant drug, compared to mirtazapine monotherapy, according to a 2007 study. Abilify can usually be taken with or without food.Ībilify can work alone for other disorders, but for depression, it’s most effective as an add-on treatment or part of augmentation therapy.Īntidepressants are the main treatment for depression, but only one-third of patients will reach remission with their initial treatment, according to 2008 research. There are different forms of Abilify, but it’s usually taken orally in the form of tablets that are swallowed whole. It’s also FDA-approved to treat symptoms of: The main active drug in Abilify, aripiprazole, is used to treat schizophrenia, according to the National Alliance of Mental Illness (NAMI). It’s not approved for this use among children. This is why it’s usually included as part of augmentation therapy, when drugs are combined. The FDA has approved Abilify as an adjunctive treatment for adults with major depressive disorder (MDD) without psychotic symptoms and when antidepressants alone aren’t enough.Ībilify is often used alongside antidepressants. Second-generation antipsychotics’ effect on 5-HT-2a receptors may be linked to lower neurological side effects. Second-generation antipsychotics may have fewer side effects than first-generation drugs. Some work by blocking the action of dopamine on the receptors of specific neurons in the brain. It’s an atypical antipsychotic drug, according to the Food and Drug Administration (FDA).Ītypical antipsychotics are second-generation antipsychotics. Abilify is a brand-name medication of the prescription drug aripiprazole.
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